Synthesis and Characterization of New Silver (I) N-Heterocyclic Ccarbene Ccomplex Dderived from Imidazol-2-ylidene salt
DOI:
https://doi.org/10.23851/mjs.v28i2.500Keywords:
Heterocyclic carbene, Silver complexesAbstract
A new N, N'-imidazolium salt 1-(2,6-diisopropylphenyl)-3- (4,6-dimorpholino -1,3,5-traizine-2-yl)-1H-imidazol-3-ium chloride) as a precursor of N - heterocyclic carbene ligand was prepared via the reaction of 1 - (2, 6 - diisopropyl phenyl - 1H - imidazole) with 1, 3, 5 - triazine derivative bearing morpholine substituent (2, 6 -dimorpholine - 6- chloro-1, 3, 5-triaziazine). Linear coordi-nated Ag (І) NHC complex was synthesised via deprotonation of the imidazolium salt and reac-tion with Ag2O in darkness at room temperature by in situ method. The complex was synthesised for using as transfer agent to prepare another transition metals complexes by transmetallation method in the future. The imidazolium salt and their silver complex have been characterized by 1 H and 13C NMR spectroscopy as well as mass spectrometry.Downloads
References
Rowan, M. P. ; Cancio, L. C. ; Elster, E. A. ; Burmeister, D. M. ; Rose, L. F. ; Natesan, S. and Chung, K. K. Burn wound healing and treatment: review and advancements. Critical care, 2015.19, 243.
Barret, J. P. ; Herndon, D. N. Effects of burn wound excision on bacterial coloniza-tion and invasion. Plast Reconstr Surg 2003; 111 (2): 744-50; discussion 751-752.
McCulloh, R. J. Biomarkers in Sepsis and Severe Infection: Where Immunology Meets Diagnostics.2012. J Immunodefic Disor 2012, 1: 1.
Castelli, G. P. ; Pognani, C. ; Meisner, M. ; Stuani, A., Bellomi, D. and Sgarbi, L. Pro-calcitonin and C-reactive protein during systemic inflammatory response syndrome, sepsis and organ dysfunction. Crit Care.2004 Aug; 8 (4): R234-42.
Aabenhus, R.1; Jensen, J. U. Procalciton-inguided antibiotic treatment of respiratory tract infections in a primary care setting: are we there yet? Prim Care Respir J.2011 Dec, 20 (4): 360-7.
Mohammed H.
Synthesis and Characterization of New Silver (I) N-Heterocyclic Ccarbene Ccomplex Dderived from Imidazol-2-ylidene salt201762
Caliendo, A. M.1; Gilbert, D. N. ; Ginoc-chio, C. C. ; Hanson, K. E. ; May, L. ; Quinn, T. C. ; Tenover, F. C. ; Alland, D. ; Blaschke, A. J. ; Bonomo R. A., Carroll, K. C. ; Ferraro, M. J. ; Hirschhorn, L. R. ; Joseph, W. P. ; Karchmer T. ; MacIntyre, A. T. ; Reller, L. B. and Jackson, A. F. In-fectious Diseases Society of America (ID-SA). Better tests, better care: improved di-agnostics for infectious diseases. Clin In-fect Dis.2013 Dec;57 Suppl 3: S139-70.
Mohan, A. and Harikrishna, J. Biomarkers for the diagnosis of bacterial infections: in pursuit of the ‘Holy Grail’Indian J Med Res.2015 Mar; 141 (3): 271–273.
Mokline, A. ; Garsallah, L. ;Rahmani, I. ; Jerbi, K. ; Oueslati, H. ; Tlaili, S. ; Ham-mouda, R. ; Gasri, B. and Messadi, A. A. Procalcitonin: a diagnostic and prognostic biomarker of sepsis in burned patients. Ann Burns Fire Disasters.2015 Jun 30;28 (2): 116-20.
Rosanova, M. T. ; Tramonti, N. ; Taicz, M. ; Martiren, S. ; Basilico, H. ; Signorelli, C. and Lede, R. Assessment of C-reactive protein and procalcitonin levels to predict infection and mortality in burn children. Arch Argent Pediatr, 2015.113 (1), 36-41.
Kim, H. S. ; Yang, H. T. ; Hur, J. ; Chun, W. ; Ju, Y. S. ; Shin, S. H. and Lee, K. M. Procalcitonin levels within 48 hours after burn injury as a prognostic factor. Ann Clin Lab Sci, 2012.42 (1), 57-64.
Nakae, H. ; Inaba, H. and Endo, S. Useful-ness of procalcitonin in Pseudomonas burn wound sepsis model. Tohoku J Exp Med.1999 Jul;188 (3): 271-3.
Tahir, S1. ; Memon, A. R. ; Kumar, M. and Ali, S. A. Prediction of mortality after ma-jor burn: physiological versus biochemical measures. Wounds.2009 Jul; 21 (7): 177-82.
Zarei, M. R.1; Dianat, S. ; Eslami, V. ; Harirchi, I. ; Boddouhi, N. ; Zandieh A. and Rasouli, M. R. Factors associated with mortality in adult hospitalized burn pa-tients in Tehran. Ulus Travma Acil Cerrahi Derg, 2011. Jan;17 (1): 61-5.
Moore, E. C. ; Pilcher, D. V. ; Bailey, M. J. ; Stephens, H. and Cleland, H. The Burns Evaluation and Mortality Study (BEAMS): predicting deaths in Australian and New Zealand burn patients admitted to intensive care with burns. Journal Trauma Acute Care Surg, 2013. Aug;75 (2): 298-303.
Zhao, D. ; Zhou, J. ; Haraguchi, G. ; Arai, H. and Mitaka, C. Procalcitonin for the dif-ferential diagnosis of infectious and non-infectious systemic inflammatory response syndrome after cardiac surgery. J Intensive Care, 2014. Jun 3;2: 35.
Klingele, M. ; Bomberg, H. ; Poppleton, A. ; Minko, P. ; Speer, T. ; Schäfers, H. J. and Groesdonk, H. V. Elevated procalcitonin in patients after cardiac surgery: a hint to nonocclusive mesenteric ischemia. Ann Thorac Surg, 2015. Apr;99 (4): 1306-12.
Barati, M. ; Alinejad, F. ; Bahar, M. A. ; Tabrisi, M. S. ; Shamshiri, A. R. ;Bodouhi, N. O. ; and Karimi, H.comparison of WBC, ESR, CRP and PCT serum levels in septic and non-septic burn cases. Burns, 2008.34 (6), 770-774.
Seoane, L. ; Pertega, S. ; Galeiras, R. ; As-tola, I. ; and Bouza, T. Procalcitonin in the burn unit and the diagnosis of infection. Burns, 2014.40 (2), 223-229.
Mann, E. A. ; Wood, G. L. ; and Wade, C. E. Use of procalcitonin for the detection of sepsis in the critically ill burn patient: a systematic review of the literature. Burns, 2011.37 (4), 549-558.
Von Heimburg, D., Stieghorst, W., Khorram-Sefat, R. and Pallua, N. Procalci-tonin—a sepsis parameter in severe burn injuries. Burns, 1998.24 (8), 745-750
Neely, A. N. ; Smith, W. L. ; and Warden, G. D. Efficacy of a rise in C-reactive pro-tein serum levels as an early indicator of sepsis in burned children. J Burn Care Re-habil, 1998.19 (2), 102-105. [22] Alkazaz F. F. ; Abdulsattar S. A. ; Farred F. A. and Mahmood S. J. Risk factor of metabolism alteration in burn patients. SENRA Academic Publishers, British Co-lumbia, 2014. Vol.8, No.3, pp.3057-3060, [23] Jeschke, M. G. ; Finnerty, C. C. ; Kulp, G. A. ; Kraft, R. ; and Herndon, D. N. Can we use C-reactive protein levels to predict se-
Al-Mustansiriyah Journal of Science
ISSN: 1814-635X (print), ISSN: 2521-3520 (online) Volume 28, Issue 2, 2017 DOI: http://doi.org/10.23851/mjs.v28i2.xxx
Copyright © 2017 Authors and Al-Mustansiriyah Journal of Science. This work is licensed under a Creative Commons Attribution-
NonCommercial 4.0 International Licenses.
vere infection or sepsis in severely burned patients? International Journal of Burns and Trauma, 2013.3 (3), 137-143. [24] Lavrentieva, A. ; Kontakiotis, T. ; Laz-aridis, L. ; Tsotsolis, N. ; Koumis, J. ; Kyr-iazis, G. ; and Bitzani, M. Inflammatory markers in patients with severe burn inju-ry. What is the best indicator of sepsis? Burns, 2007.33 (2), 189-194. [25] Neely, A. N. ; Fowler, L. A. ; Kagan, R. J. ; and Warden, G. D. Procalcitonin in pedi-atric burn patients: an early indicator of sepsis? Journal Burn Care Rehabil, 2004.25 (1), 76-80. [26] Sachse, C. ; Machens, H. G. ; Felmerer, G. ; Berger, A. ; and Henkel, E. Procalcitonin as a marker for the early diagnosis of se-vere infection after thermal injury. J Burn Care Rehabil, 1999.20 (5), 354-360.
Downloads
Key Dates
Published
Issue
Section
License
Articles accepted for publication in Al-Mustansiriyah Journal of Science (MJS) are protected under the Creative Commons Attribution 4.0 International License (CC BY-NC). Authors of accepted articles are requested to sign a copyright release form prior to their article being published. All authors must agree to the submission, sign copyright release forms, and agree to be included in any correspondence between MJS and the authors before submitting a work to MJS. For personal or educational use, permission is given without charge to print or create digital copies of all or portions of a MJS article. However, copies must not be produced or distributed for monetary gain. It is necessary to respect the copyright of any parts of this work that are not owned by MJS.
How to Cite
