Synthesis, Characterization and Biological Activity of Some Mixed Ligand Complexes of 1, 10-Phenanthronline and [4-(2-hydroxy-1,2-diphenylethylideneamino)-N-pyrimidin-2-yl) benzene sulfonamide] with Divalent Metal Ions

Rehab K. Al-Shemary; Inam H. Ibrahim; Nibras A. Al-marsomy

doi:10.23851/mjs.v27i5.168

Authors

Rehab K. Al-Shemary Department of Chemistry, College of Education for Pure Sciences, Ibn-Al-Haitham, University of Baghdad
Inam H. Ibrahim Department of Chemical industries, Technology institute, Baghdad
Nibras A. Al-marsomy Department of Chemical industries, Technology institute, Baghdad

DOI:

https://doi.org/10.23851/mjs.v27i5.168

Keywords:

Schiff base, benzoin, Characterization, Mixed ligand complexes.

Abstract

Schiff base ligand [4-(2-hydroxy-1, 2-diphenylethylideneamino)-N-pyrimidin-2-yl)benzene sulfonamide] (L) was prepared through a condensation reaction of sulfadiazine and benzoin in acidic medium. The prepared ligand has been characterized with different techniques (C.H.N.S, FT-IR, UV-Vis and¹H&¹³C-N.M.R). Mixed ligand complexes of some divalent metal ions [Co^(II), Mn^(II), Ni^(II),Cu^(II) and Hg^(II)] were prepared by the reaction of [4-(2-hydroxy-1,2-diphenylethylidene amino)-N-pyrimidin-2-yl)benzene sulfonamide](L) and 1,10-Phenanthronline with the metal ions in basic conditions. The prepared complexes were characterized and their astrochemical structures and geometries were suggested depending upon data of (UV-Vis, FT-IR, atomic absorption, micro elemental analysis The following general formula was achieved : [M(PHN)(L)₂], where M represent (Co^(II)- Cu^(II)-Mn^(II)- Ni^(II) and Hg^(II)). Electronic spectra supported by magnetic moment's revealed octahedral geometries for all the prepared complexes. The mixed complexes showed resistivity to different bacteria such as(Pseudomonas aeruginosa), (Bacillus subtilis), (Escherichia coli), and (staphylococcus aureus).

References

A.A Emara, A Azza, A Abou-Hussen ", Spectroscopic studies of bimetallic complexes derived from tridentate or tetradentate Schiff bases of some di- and tri-valent transition metals," Spectrochim. Acta Part A, p. 1010–1024, 2006.

https://doi.org/10.1016/j.saa.2005.09.010

PMid:16332449

J TAswar and AS Makode, "Synthesis, characterization, biological and thermal properties of some new Schiff base complexes derived from 2-hydroxy-5-chloro-acetophenone and S-methyl dithiocarbazate,," Indian J. chem, vol. ; 43, no. A, pp. 2120-2125., 2004.

M Ravanasiddappa, T Sureshg, K Syed, S C Radhavendray, C Basavaraja and S DAngadi, "Transition Metal Complexes of 1, 4 (2-Hydroxyphenyl -1-yl) Diimmino Azine, Synthesis, Characterization and Antimicrobial Studies," E-J. chem, vol. 5, no. 2, pp. 395-403, 2008.

https://doi.org/10.1155/2008/328961

M. Raju, "Synthetic, structural and biological Properties of binuclear complexes with some Schiff bases," vol. 64, no. 4, pp. :345-353, 2007.

K.Tahir, S.Minnat and A, Transition metal ion directed bimetallic macrocyclic complexes, Trans. Met. Chem., vol. ; 24, pp. : 669 -671, 1999.

J Balsells, L Mejorado, M. Phillips, F Ortega, G Aguirre, RSomanathan and P.J Walsh, "Synthesis of Chiral Sulfonamide/Schiff Base Ligands, " Tetrahedron Asymm, vol. 9, 1998.

M Kojima,H. Taguchi, M. Tsuchimoto and K Nakajima, Coordination Chemistry Reviews, vol. 237, 2003, pp. 183-196.

https://doi.org/10.1016/S0010-8545(02)00227-8

NJ Long, "Organometallic compounds for nonlinearoptics:the search for en-lightenment Angewandte.," Chem. Inter.Ed, vol. 34, no. 21, 1995.

MLD, Rotondo and E A Rotondo, "NMR Study of L-ShapedQuinoxaline Platinum(II)Complexes-Crystal structure of [Pt(DMeDPQ)(bipy)](PF6) 2," Eur. J. Inorg. Chem, pp. 4710 - 4717, 2004;.

E. G. a. M. LG, Advances inInorganic Biochemistry Models in Inorganic Chemistry, PTR prentice-Hall, Inc, 1994.

K. Burger "Coordination Chemistry Experimental Methods," 1973.

A R Chakravarty, AP Nreddy, BK Santra and AM Thomas, "Copper Complexes as Chemical Nucleases," J. Indian. Chem. Sci., Vols. 114,, pp. 319-401., 2002.

https://doi.org/10.1007/bf02703829

BP. Lever, Inorganic Electronic spectroscopy, Elsevier, 1984.

S. S Chandra and J Sangeetika, "EPR and electronicspectruml studies on copper(II) complexes of some N-O donor ligands," J. Indian Chem. Soc, no. 81, pp. 203-206, 2004.

J. Sima, "Mechanism of Photoredox Reactions of Iron(III)Complexes Containing Salen-type Ligands," Crao. Chem. Acta, vol. 593, p.., 2001.

S.Ren,R.Wang,K. Komastu, P.BKrause, Y.Zyrianov, C. EMckenna, C.Csipke, Z. A,Tokes and E. J Lien S, "Synthesis, biological evaluation, and quantitative structure-activity relation ship analysis of new Schiff bases of hydroxy semicarbazide as potential antituamor agents," J.Med. Chem., vol. 45, no. 410, 2002.

T. S., . K. S., . S. C. R., . C. B. a. S. D. A. M Ravanasiddappa, ", "Transition Metal Complexes of 1, 4 (2-Hydroxyphenyl -1-yl) Diimmino AzineSynthesis, Characterization and Antimicrobial Studies," E-J. chem, vol. 2, pp. 395-403, 2008.