TORCH Screening Test in Pregnant Women of Kirkuk City

Authors

  • Hiro M. Obaid Medical Laboratory Techniques department, College of Technology, Northern Technical University, Kirkuk
  • Shawbow A. Juma Azady Teaching Hospital, Laboratories Department, Kirkuk

DOI:

https://doi.org/10.23851/mjs.v27i5.162

Keywords:

TORCH screening, Pregnant women, Kirkuk city.

Abstract

In the course of pregnancy, the developing fetus might have some infections that can be transmit to him transplacentally from his mother. Early identification and treatment of these infections in a neonates is essential. Prenatal caution comprehends a range of tests, involving a TORCH screen test.

From the beginning of July till the end of December 2014. 500 blood samples were collected for TORCH screening from pregnant women whom attended virology section in Azadi Teaching Hospital. The TORCH screening was performed using ELISA technique.

The result of  TORCH screening tests was not differed significantly between year 2013 and 2014, but there was significant differences between the frequency of the microorganisms included in TORCH screening, the highest was for Cytomegalovirus and Rubella with rates of 29.2, 39.1 % and 30.3, 41.8 % for each of the two viruses respectively. Lower frequency was observed for Toxoplasma with rate of 9.5, 8.9 % followed by    Herpes simplex virus with a rate of  only 1.1, 2.6 %. High rate of mixed infection were between Cytomegalovirus and Rubella. The frequency of chronic infections were significantly higher comparing with acute and subacute cases. The rate of infections was not effected by patients age.

Cytomegalovirus, Rubella and Toxoplasma are prevalent among pregnant women in Kirkuk city and probably they are the causative agents of abortion and infertility found among them, therefore it's better for pregnant woman or those planning to become pregnant to be tested for TORCH infections, and vaccinated against Rubella, Cytomegalovirus, Herpes simplex virus and Toxoplasma to grantee her health  as well as her baby.

Downloads

Download data is not yet available.

References

Padmavathy M, Mangala G, Malini J, Umapathy BL, Navaneeth BV, Mohit Bhatia and Shruthi H. Seroprevalence of TORCH Infections and Adverse Reproductive Outcome in Current Pregnancy with Bad Obstetric History. J Clin Biomed Sci. 2013 ; 3 (2):62-71.

Sadik MS, Fatima H, Jamil K and Patil C. Study of TORCH profile in patients with bad obstetric history. Biolo Medi j. 2012; 4 (2): 95-101.

Binnicker MJ, Jespersen DJ and Harring JA. Multiplex detection of IgM and IgG class antibodies to Toxoplasma gondii, Rubella virus, and Cytomegalovirus using a novel ltiplex flow immunoassay. Clin Vaccine Immunol. 2010; 17(11): 1734 1738.

Janak Kishore1, Richa Misra1, Abhiruchi Paisal and Yashodhra Pradeep . Adverse reproductive outcome induced by Parvovirus B19 and TORCH infections in women with high-risk pregnancy. J Infect Dev Ctries. 2011; 5(12):868-873.

Sandra K. Halonen1 and Louis M. Weiss2 Toxoplasma gondii Presentations at the 10th International Workshops on Opportunistic Protists: 100 Years and Counting. Eukaryot Cell j. 2009; 8(4): 437–440.

Vijayalakshmi P, Anuradha R, Prakash K, Narendran K, Ravindran M and Prajna L. Rubella serosurveys at three Aravind eye hospitals in Tamil Nadu, India. Bull World Health Organ. 2004; 82:259-64.

Stagno S and Britt W. Cytomegalovirus infections. In: Infectious Diseases of the Fetus and Newborn Infant, 6th ed, Remington, JS, Klein, JO, Wilson, CB, Baker, CJ (Eds), Elsevier Saunders, Philadelphia. 2006; p.739.

Schiffer JT, Mayer BT, Fong Y, Swan DA and Wald A. Herpes simplex virus-2 transmission probability estimates based on quantity of viral shedding. J R Soc Interface.2014;11 (95):140-160.

Mohammad Esraa A and Salman Yahya J. Study of TORCH infections in women with Bad Obstetric History (BOH) in Kirkuk city. Int.J.Curr.Microbiol.App.Sci. 2014; 3(10): 700-709

Salman Yahya J. Role of Toxoplasma gondii and Human Herpes Simplex Virus Type-2 in Women with Abortions and Congenital Abnormalities in Kirkuk City. Int. J. Curr. Res. Biosci. Plant Biol. 2014; 1(2): 1-8.

Aljumaili Z K and Alsamarai A M and Najem WS. Seroprevalence of Herpes Simplex Virus Type 2 (HSV 2) in Women with Bad Obstetric History. Amer J Derm Venereol. 2013; 2(3): 31-38.

Jasim M, Majeed H A and Ali I A. Performance off Serological Diagnosis of TORCH Agents in Aborted versus non aborted Women of Wasett province in Iraq. Tikrit Med J. 2011; 17(2): 141-147.

Mahdi B M, Saour M Y and Salih W H. Cytomegalovirus infection in infertile women. J Experi Integ Med. 2011; 1(4):273-276.

Al-Jeboori K H. Serlogical diagnosis of anti-Rubella and anti-Cytomegalovirus (IgM and IgG) in iraqi women sera using the enzyme linked fluorescent assay (elfa). I.J.S.N. 2013; 4(3): 530-532.

Kamal S A, Awadh R M and Al-Marzoqi A H. Genetic Study of TORCH Infections in Women with Bad Obstetric History: Multiplex Polymerase Chain Reaction for Detection of Common Pathogens and Agents of Congenital Infections. J Biolo Agri Heal. 2013; l3(18): 49-53.

Shashi C, Usha A and Aruna A. Prevalence of IgM Antibodies to Toxoplasma, Rubella and Cytomegalovirus Infections during Pregnancy. JK SCI. 2004; 6(4):190-93.

Devi K S, Devi Y G, Singh N S, Singh A M and Singh I D. Seroprevalence of TORCH in women with still birth in RIMS hospital. J Med Soci. 2008; 22: 2-4.

Karad D and Kharat A. Seroprevalence of Torch Infections in Bad Obstetrics History in HIV and Non-HIV Women in Solapur District of Maharashtra India. J Hum Virol Retrovirol.2015; 2(7):1-7.

Abu-Madi M A, Behnke J M and Dabritz H A. Toxoplasma gondii Seropositivity and Co-Infection with TORCH Pathogens in High-Risk Patients from Qatar. Am. J. Trop. Med. Hyg.2010; 82(4): 626–633.

Turbadkar D, Mathur M and Rele M. Seroprevalence of torch infection in bad obstetric history. Indian J Med Microbiol. 2003; 21: 108-10.

Janak K, Richa M, Abhiruchi P and Yashodhra P. Adverse reproductive outcome induced by parvovirus B19 and TORCH infections in women with high risk pregnancy. J Infect Dev Ctries. 2011; 5(12):868-730.

Kaneshiro N. TORCH Screen. Medline Plus. Retrieved on May 28, 2012, from http://www.nlm.nih.gov/medlineplus/ency/ article /003350.

Downloads

Key Dates

Published

06-07-2017

Issue

Section

Original Article

How to Cite

[1]
H. M. Obaid and S. A. Juma, “TORCH Screening Test in Pregnant Women of Kirkuk City”, Al-Mustansiriyah Journal of Science, vol. 27, no. 5, pp. 17–25, Jul. 2017, doi: 10.23851/mjs.v27i5.162.

Similar Articles

1-10 of 78

You may also start an advanced similarity search for this article.