Relationship of Obesity to Serum Ferritin, Lipid Profile, uric acid and urea at Obesity Medical Center in Iraq
Keywords:Obesity, ferritin, lipid profile, Body Mass index, Obesity complications.
AbstractObesity is a hyper assembly of energy in the form of adipose tissues which has worse effects on health. The major factors of obesity epidemic are: heavy mails which are rich in lipids, carbohydrates resulting in overweight and eventually obesity, decrease in physical activity that lead to defect in calories conception. In health care facilities ferritin assay is used as a screening test to detect iron deficiency; however, its reliability in obesity has been questioned. The aim of present study was to assess and compare the incidence of obesity, hyperferritinemia, hyperlipidemia and hypouricemia among middle-aged hypertensive patients in the local setting as well as, examined ferritin concentrations and other classical indices in obese males and females. This limited population study was conducted at Obesity Medical Center at Al-Kindy Teaching Hospital, Baghdad, Iraq from January to march 2016. One hindered and eight patients were enrolled in this study plus to participate of 61 subjects as healthy control. On the basis of body mass index (BMI), 169 participants were divided into two groups: BMI ≥ 18.5–25 kg/m2 non obese (control), BMI ≥ 30 kg/m2 obese subjects. The main demographic features data of the study population appears that systolic blood pressure and diastolic blood pressure were raised significantly in obese patients (P<0.05) compared with control. Serum hemoglobin level was decreased significantly in obese male when compared with the nonobese group and no difference in the female group was observed. In addition, the levels of lipid profile and other studied parameters according to gender showed the following results: A significant elevation in TG, LDL, VLDL, glucose, ferritin in obese (for both genders) compared with the non-obese group. While a significant decrease was noticed in HDL-c, uric acid and urea level in obsess group compared with the non-obese group in both genders. The comparison results between obese males and females concluded that a significant elevation in BMI with a significant decrease in VLDL and ferritin levels in obese females compared with obese males. The present study includes examined all types of correlation between parameters. In obese patients (n=108), stepwise linear regression analysis showed that, serum ferritin levels were independently correlated with LDL, VLDL levels and age, (P< 0.001).
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