Mycotoxins Hazard Assessment of Feedstuffs from Multiple Sources Products Commercially Imported for Iraq
Keywords:Mycotoxins contamination, Risk assessment, animal feedstuffs, Regulations & policy
Contamination feedstuffs with fungi or their metabolites toxins poses considerable hazard to public health and animal welfare. The information on mycotoxins identified from a variety of feedstuff in 2021 (soyabean, maize, fish meals, and poultry pellets) was retrieved from archive papers documented in the Centre of Standardization and Quality Control/Department of Agriculture. A total of 1325 samples feedstuff were examined by this Centre using the direct ELISA test to detect aflatoxins, ochratoxin, and trichothecene. The aflatoxin was identified in 67 (5.05%) samples followed by ochratoxin in 52 (3.92%) samples and Trichothecene (T2) in 50 (3.77) samples. Additionally, the results were showed the co-infection/co-occurrence of mycotoxins from positive samples of soyabean, fish meals, and poultry pellet, although this contamination within acceptable level. Only two samples of poultry feed were determined to have contamination levels above the acceptable limit, as 21ppb with aflatoxins and 19ppb with ochratoxin contamination. The moisture levels were also measured for these commodities by NIR apparatus. From statistics outputs, the squared correlation coefficient (R2) did not share too much variability between moisture and degree of contamination with three mycotoxins identified. The study concluded that mycotoxins remain to be a concern for global health, and their residues in animal feed are important in terms of health safety standards that propose adhering to food chain regulations in commercial markets.
J. W. Bennett, M. Klich. Mycotoxins. Clinical microbiology reviews, 16(3): 497-516, 2003.
R. A. El-Sayed, A. B. Jebur, W. Kang, M. A. A. B. El-Esawi, F. M. El-Demerdash, An overview on the major mycotoxins in food products: characteristics, toxicity, and analysis. Journal of Future Foods, 2(2): 91-102,2022.
M. D. Kumar, S. N. Kotwaliwale, K. K. Singh. Critical factors responsible for fungi growth in stored food grains and non-Chemical approaches for their control. Industrial Crops and Products, 108, 162-182,2017.
M. R. Alina. Implications of Mycotoxins in Food Safety. In Mycotoxins and Food Safety-Recent Advances. 2022.
P. Karlovsky, M. Suman, F. Berthiller, J. De Meester, G. Eisenbrand, I. P. Perrin Oswald, G. Speijers, A. Chiodini, T. Recker, P. Dussort. Impact of food processing and detoxification treatments on mycotoxin contamination Mycotoxin Research, 32(4) : 179-205, 2016.
C. G. Awuchi, I. O. Amagwula, P. Priya, R. Kumar, U. Yezdani, M. G. Khan. Aflatoxins in foods and feeds: A review on health implications, detection, andcontrol. Bulletin of Environment, Pharmacology and Life Sciences, 9, 149-155,2020.
C. G. Awuchi, E. N. Ondari, C. U. Ogbonna, A. K. Upadhyay, K. Baran, C. O. Okpala, R. P. Guiné. Mycotoxins affecting animals, foods, humans, and plants: Types, occurrence, toxicities, action mechanisms, prevention, and detoxification strategies-A revisit. Foods, 10(6): 1-48,2021.
R. Baan, Y. Grosse, K. Straif, B. E. Secretan, F. El Ghissassi, V. Bouvard. A review of human carcinogens-part F: chemical agents and related occupations. The lancet Oncology, 10(12): 1143-1144, 2009.
K. Bordin, M. M. Sawada, C. E. D. Rodrigues., C. R. da Fonseca, C.A.F. Oliveira. Incidence of aflatoxins in oil seeds and possible transfer to oil: a review. Food Engineering Reviews, 6(1): 20-28, 2014.
E. Azziz-Baumgartner, K. Lindblade, K. Gieseker, H. S. Rogers, S. Kieszak, H. Njapau. Aflatoxin Investigative Group. Case-control study of an acute aflatoxicosis outbreak, Kenya, 2004. Environmental Health Perspectives, 113(12): 1779-1783,2005.
E. Streit, G. Schatzmayr, P. Tassis, E. Tzika, D. Marin, I. Taranu, C. Tabuc, A. Nicolau, I. Aprodu, O. Puel, I. P. Oswald. Current situation of mycotoxin contamination and co-occurrence in animal feed-Focus on Europe. Toxins, 4(10): 788-809,2012.
S. Marin, A. J. Ramos, G. Cano-Sancho, V. Sanchis. Mycotoxins: Occurrence, toxicology, and exposure assessment. Food and Chemical Toxicology, 60, 218-237.2013.
M. E. B. da Rocha, F. D. C. O. Freire, F. E. F. Maia, M. I. F. Guedes, D. Rondina. Mycotoxins and their effects on human and animal health. Food Control, 36(1): 159-165, 2014.
J. D. Groopman, T. W. Kensler, F. Wu. Food Safety: Mycotoxins-Occurrence and Toxic Effects. In Encyclopedia of human nutrition (pp. 337-341). Elsevier Inc, 2012.
A. G. Marroquín-Cardona, N. M. Johnson, T. D. Phillips, A.W. Hayes. Mycotoxins in a changing global environment-a review. Food and Chemical Toxicology, 69, 220-230, 2014.
M. E. Zain. Impact of mycotoxins on humans and animals. Journal of Saudi Chemical Society, 15(2): 129-144, 2011.
D. El Khoury, S. Fayjaloun, M. Nassar, J. Sahakian, P.Y. Aad . Updates on the Effect of Mycotoxins on Male Reproductive Efficiency in Mammals. Toxins, 11(9): 1-21,2019.
W. S. Darwish, R. M. E. Bayomi, A. M. A El-Moaty, T. M. Gad. Mould contamination and aflatoxin residues in frozen chicken meat-cuts and giblets. Japanese Journal of Veterinary Research, 64(2): S167-S171,2016.
S. Gbashi, N. E. Madala, S. De Saeger, M. De Boevre, I. Adekoya,O. A. Adebo, P. B. Njobeh. The Socio-Economic Impact of Mycotoxin Contamination in Africa. In P. B. Njobeh, F. Stepman (Eds.), Mycotoxins - Impact and Management Strategies. 2019.
CAST Report. Mycotoxins: risks in plant, animal, and human systems. In: Richard, J.L., Payne, G.A. (Eds.), Council for Agricultural Science and Technology Task Force Report No. 139, Ames, Iowa, USA,2003.
V. L. Pereira, J. O Fernandes, S.C. Cunha. Mycotoxins in cereals and related foodstuffs: A review on occurrence and recent methods of analysis. Trends in Food Science & Technology, 36(2): 96-136, 2014.
D. A. Abdou, R. M. Othman, N. E. El-Bordeny, N. A. Ibrahim, M. A. Abouzeid. Monitoring imported grain-based ingredients used in feed processing for toxigenic moulds and naturally occurring mycotoxins. The Egyptian Journal of Experimental Biology, 15, 145-154,2016.
G. S. Shephard. Current status of mycotoxin analysis: a critical review. Journal of AOAC International, 99(4): 842-848, 2016.
F. Fumagalli, M. Ottoboni, L. Pinotti, F. Cheli. Integrated Mycotoxin Management System in the Feed Supply Chain: Innovative Approaches. Toxins, 13(8): 1-35, 2021.
M. Mannaa, K.D. Kim. Influence of Temperature and Water Activity on Deleterious Fungi and Mycotoxin Production during Grain Storage. Mycobiology, 45(4): 240-254, 2017.
Y. Hoffmans, S. Schaarschmidt, C. Fauhl-Hassek, H. J. van der Fels-Klerx. Factors during Production of Cereal-Derived Feed That Influence Mycotoxin Contents. Toxins, 14(5): 1-27, 2022.
H. Wu, T.W. Ng, J.W. Wong, K. M. Lai. Environmental Sustainability and Mould Hygiene in Buildings. International Journal of Environmental Research and Public Health, 15(4): 1-14, 2018.
R. Albarakat, M. Le, V. Lakshmi. Assessment of drought conditions over Iraqi transboundary rivers using FLDAS and satellite datasets. Journal of Hydrology: Regional Studies, 41, 1-20, 2022.
P. M. Mazumder, D. Sasmal. Mycotoxins-limits and regulations. Ancient science of life, 20(3): 1-19, 2001.
H. P. van Egmond, R. C. Schothorst, M.A. Jonker. Regulations relating to mycotoxins in food. Analytical and Bioanalytical Chemistry, 389(1): 147-157, 2007.
FAO. 2004. Worldwide regulations for mycotoxins in food and feed. FAO Food and Nutrition, Rome.
J. Singh, A. Mehta. Rapid and sensitive detection of mycotoxins by advanced and emerging analytical methods: A review. Food Science & Nutrition, 8(5): 2183-2204,2020.
C. H. Rodríguez-Cervantes, A. J. Ramos, M. L. Robledo-Marenco, V. Sanchis, S. Marín, M.I. Girón-Pérez. Determination of aflatoxin and fumonisins levels through ELISA and HPLC, on tilapia feed in Nayarit, Mexico. Food and Agricultural Immunology, 24(3): 269-278,2013.
C. Li, Y. L. Wu, T. Yang, W.G. Huang-Fu. Rapid determination of fumonisins B1 and B2 in corn by liquid chromatography-tandem mass spectrometry with ultrasonic extraction. Journal of Chromatographic Science, 50(1): 57-63,2012.
L. Xie, M. Chen, Y. Ying.Development of methods for determination of aflatoxins. Critical Reviews in Food Science and Nutrition, 56(16): 2642-2664,2016.
M. Niyibituronsa, A. N. Onyango, S. Gaidashova, S. M. Imathiu, M. Uwizerwa, I. Wanjuki, J. Harvey. Evaluation of mycotoxin content in soybean (Glycine max L.) grown in Rwanda. African Journal of Food, Agriculture, Nutrition and Development, 18(3): 13808-13824,2018.
M. D. L. Souza, M. Sulyok, O. Freitas-Silva, S.S. Costa, C. Brabet, M. Machinski Junior, R. Schuhmacher. Cooccurrence of mycotoxins in maize and poultry feeds from Brazil by liquid chromatography/tandem mass spectrometry. The Scientific World Journal, 2013, 1-9,2013.
S. M. Mokubedi, J. Z. Phoku, R. N. Changwa, S. Gbashi, P.B. Njobeh. Analysis of Mycotoxins Contamination in Poultry Feeds Manufactured in Selected Provinces of South Africa Using UHPLC-MS/MS. Toxins, 11(8): 1-17, 2019.
M. Sokolović, B. Šimpraga. Survey of trichothecene mycotoxins in grains and animal feed in Croatia by thin layer chromatography. Food Control, 17(9): 733-740, 2006.
E. O. Oni, C. A. Komolafe, A.O.Badmos, S. O. Kareem, M. A. Waheed, F. Oluwafemi. Reduction of aflatoxin in freshly harvested maize using solar dryers. Journal of the Science of Food and Agriculture. 102 (11): 4791-4801,2022.
R. Suleman, A. Amjad, A. Ismail, S. Javed, U. Ghafoor, S. Fahad. Impact of plastic bags usage in food commodities: an irreversible loss to environment. Environmental Science and Pollution Research, 29, 49483-49489, 2022.
K. A. Scudamore, M.T. Hetmanski, H. K. Chan, S. Collins. Occurrence of mycotoxins in raw ingredients used for animal feeding stuffs in the United Kingdom in 1992. Food Additives & Contaminants, 14(2): 157-173,1997.
A. Goertz, S. Zuehlke, M. Spiteller, U. Steiner, H. W. Dehne, C. Waalwijk, E. C. Oerke. Fusarium species and mycotoxin profiles on commercial maize hybrids in Germany. European Journal of Plant Pathology, 128(1): 101-111, 2010.
A. Huwig, S. Freimund, O. Käppeli, H. Dutler. Mycotoxin detoxication of animal feed by different adsorbents. Toxicology Letters, 122(2): 179-188, 2001.
H. Shanakhat, A. Sorrentino, A. Raiola, A. Romano, P. Masi, S. Cavella. Current methods for mycotoxins analysis and innovative strategies for their reduction in cereals: An overview. Journal of the Science of Food and Agriculture, 98(11): 4003-4013, 2018.
M. Liu, L. Zhao, G. Gong, L. Zhang, L. Shi, J. Dai and L. Sun. Invited review: Remediation strategies for mycotoxin control in feed. Journal of Animal Science and Biotechnology, 13(1): 1-16,2022.
S. Döll, S. Dänicke, H. Valenta, G. Flachowsky. In vitro studies on the evaluation of mycotoxin detoxifying agents for their efficacy on deoxynivalenol and zearalenone. Archives of Animal Nutrition, 58(4): 311-324,2004.
K. M. Selim, H. El-hofy, R. H. Khalil. The efficacy of three mycotoxin adsorbents to alleviate aflatoxin B1-induced toxicity in Oreochromis niloticus. Aquaculture International, 22(2): 523-540,2014.
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