Investigating the Efficiency of Simple Aqueous Extract of Nigella Sativa Activity Against Serratia Marcescens Bactria

Authors

  • Samir Laybi Shkhaier Assistant Lecturer, Basic sciences Dept., College of Dentistry, Mustansiriyah University. http://orcid.org/0000-0003-2452-9075
  • Muthana Anad Majid Basic ٍsciences Dept., College of Dentistry, Mustansiriyah University. http://orcid.org/0000-0002-1057-7466
  • Wathiq Mohammad Alawi Department of Pharmacy, Al-Rafidain University College
  • Jamal ِAbed Al-Fatah Basic sciences Dept., College of Dentistry, Mustansiriyah University.
  • Hayder Hameed Abd Basic sciences Dept., College of Dentistry, Mustansiriyah University. http://orcid.org/0000-0002-7345-392X

DOI:

https://doi.org/10.23851/mjs.v31i3.859

Keywords:

Nigella Sativa, Serratia marcescens, water Nigella Extract activity, Treatment of Serratia marcescens with nigella sativa.

Abstract

Nigella sativa seeds is considered as a very effective treatment for a variety of human diseases in traditional medicine worldwide with low human toxicity. Serratia marcescens pathogenic species, a Gram-negative, opportunistic bacteria, are widespread and distributed in the human environment with considered resistance to different types of antibiotics. Extraction was performed on 12.5 gm. /150 ml of Nigella seeds using rotary evaporator. Different time periods for extraction were applied (1-4 hours) with different temperature ranges of 50 °C to 60 °C performed separately for each time period. The 3 and 4 hours extraction period at 60 °C for seeds was effective against Serratia marcescens with inhibition zone of 11.18 and 12.27 mm respectively. Nigella seeds could be a promising inhibitor with enhanced activity against Serratia marcescens. Water extraction was efficient and effective at 60 °C, with extraction period of 2-3 hours for seeds. No activity recorded below this temperature.

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Key Dates

Published

20-08-2020

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Original Article

How to Cite

[1]
S. L. Shkhaier, M. A. Majid, W. M. Alawi, ِAbed Al-Fatah J., and H. H. Abd, “Investigating the Efficiency of Simple Aqueous Extract of Nigella Sativa Activity Against Serratia Marcescens Bactria”, Al-Mustansiriyah Journal of Science, vol. 31, no. 3, pp. 39–45, Aug. 2020, doi: 10.23851/mjs.v31i3.859.

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