Synthesis and Biological Evaluation of Some Pyrrolidine-2-one Derivatives

nadia azeez betti; Redha Ib. Hussain; Sahar Ab. Kadhem

doi:10.23851/mjs.v31i1.743

Authors

nadia azeez betti Materials engineering department, University of Technology
Redha Ib. Hussain Department of chemistry, Mustansiriyah University
Sahar Ab. Kadhem Department of chemistry, Mustansiriyah University

DOI:

https://doi.org/10.23851/mjs.v31i1.743

Abstract

In this research a number of pyrrolidine-2-one derivatives were prepared by lactamization of γ –butyrolactone (GBL) with hydrazine hydrate (80%) to produce (1-aminopyrrolidine-2-one) that undergoes several reactions to afford these derivatives that diagnosed by infrared, nuclear magnetic resonance and mass spectroscopy. Antibacterial activity has also been studied using some types of bacteria, some were found to have good antibacterial activity.

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Author Biography

nadia azeez betti, Materials engineering department, University of Technology

lecturer in materials department/university of technology-iraq

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