Investigation the level of IL-10 and IFN-γ in mice infected with Entamoeba histolytica and treated with earthworm powder

Authors

  • Nebrass Faleh Chachain Al-Mustansiryah University
  • Hussein Ali Jamil Al-Mustansiryah University
  • Shaima Dawood Salman Al-Mustansiryah University

DOI:

https://doi.org/10.23851/mjs.v30i1.490

Keywords:

Earthworm powder, Entamoeba histolytica, IFN-γ, IL-10

Abstract

This study was carried out to detect the effect of earthworm powder on the Entamoeba histolytica in white mice and to measure the serum of two cytokines (IFN-γ and IL-10) of infected and treated mice with earthworm powder in comparing with metronidazole drug after 3, 7 and 9 days. Result showed that the infected mice which treated with earthworm powder in a concentration of 200 mg/ml for 10 days the level of IFN-γ in serum was (170.67, 150.33 and 145.67 pg/ml) respectively compared with control group, in the earthworm powder group (none infected) level of IFN-γ after 3, 7, 9 days was (105.50, 121.50, 127.00 pg/ml) respectively, also in the metronidazole treatment group IFN-γ level after 3, 7, 9 days was (188.33, 263.50, 253.33 pg/ml) respectively compared to control group. In the treatment earthworm powder group level IL-10 after 3, 7, 9 days was (108.67, 105.67 and 103.17 pg/ml) respectively compared with control group, but in the earthworm powder group (none infected) level IL-10 after 3, 7, 9 days was (95.67, 95.83, 95.67 pg/ml) respectively, also in the metronidazole treatment group IL-10 level after 3, 7, 9 days was (109.83, 107.67, 103.33 pg/ml) respectively compared with control groups.

Author Biographies

Nebrass Faleh Chachain, Al-Mustansiryah University

Assistant Prof. in Biology department

Hussein Ali Jamil, Al-Mustansiryah University

Master of Biology in Biology department

Shaima Dawood Salman, Al-Mustansiryah University

Master of Biology in Biology department

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Published

2019-08-15

How to Cite

[1]
N. F. Chachain, H. A. Jamil, and S. D. Salman, “Investigation the level of IL-10 and IFN-γ in mice infected with Entamoeba histolytica and treated with earthworm powder”, MJS, vol. 30, no. 1, pp. 52–57, Aug. 2019.

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Section

Biological Science